By now, most horse owners have heard of Cushing’s disease in horses. Whether your horse has been diagnosed—or you’re starting to notice subtle changes—a positive diagnosis can feel overwhelming.
But here’s the truth:
👉 With the right knowledge and support, horses with Cushing’s (PPID) can live long, healthy, and comfortable lives.
Let’s break down everything you need to know—from symptoms to solutions.
What Is Equine Cushing’s Disease (PPID)?
Equine Cushing’s Disease, also known as Pituitary Pars Intermedia Dysfunction (PPID), is a condition involving dysfunction of the pituitary gland.
💡 Fun Fact:
The pituitary gland is a small, pea-sized structure located at the base of the brain, just behind the bridge of the nose. Despite its size, it plays a major role in regulating hormones throughout the body.
In horses with PPID:
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The pituitary becomes overactive
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Hormone production (especially ACTH and cortisol) increases
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Multiple body systems become affected
It’s estimated that up to 20% of older horses may develop PPID, though younger horses can be affected as well.
What Causes Cushing’s Disease in Horses?
Cushing’s is typically age-related, but the underlying cause is neurological.
Over time:
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Dopamine-producing neurons decline
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The pituitary gland loses its regulation
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Hormone production increases unchecked
In some cases, the pituitary may also become enlarged or develop a benign tumor, further contributing to the imbalance.
Common Symptoms of Cushing’s Disease in Horses
Cushing’s symptoms can develop gradually, which is why they’re often overlooked early on.
Early Signs (Often Missed):
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Delayed shedding or patchy coat
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Dry, coarse hair texture
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Loss of topline or muscle tone
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Mild lethargy or decreased performance
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Behavioral changes (irritability, aggression)
Progressive & Advanced Symptoms:
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Long, curly coat (classic PPID sign)
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Weight loss despite normal eating
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Excessive thirst (polydipsia)
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Frequent urination (polyuria)
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Excessive sweating—or lack of sweating
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Fat deposits (cresty neck, tailhead pockets)
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Recurrent infections
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Increased risk of laminitis
👉 Many owners first say: “My horse just isn’t shedding like they used to.”
Are Horses at Risk for Cushing’s?
While horses over 15 years old are most commonly affected, PPID is not limited to age alone.
Risk factors may include:
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Aging
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Metabolic stress
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Poor diet or high sugar intake
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Chronic inflammation
A forage-based diet and proper management are essential for supporting horses at risk or already diagnosed.
How Is Cushing’s Diagnosed?
Diagnosis typically involves a combination of:
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Blood testing (ACTH levels)
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Clinical symptoms
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Seasonal testing adjustments
Because hormone levels fluctuate throughout the year, your veterinarian may recommend testing during specific seasons for more accurate results.
Why Early Intervention Matters
Cushing’s is a progressive condition, meaning it worsens over time if left unmanaged.
Without support, horses are at increased risk for:
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Chronic laminitis
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Immune suppression
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Metabolic dysfunction
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Decreased quality of life
👉 Catching it early can make a huge difference in long-term outcomes.
Traditional Treatment Options
The most common pharmaceutical option is:
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Pergolide (Prascend) – supports dopamine levels and helps regulate hormone production
While effective, many horse owners choose to support the body holistically alongside (or in some cases instead of) pharmaceuticals, depending on their goals and their horse’s needs.
🌿 Natural Support for Horses with Cushing’s
Supporting a horse with PPID naturally focuses on:
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Endocrine (hormone) balance
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Immune system strength
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Circulation and detox pathways
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Coat and skin health
⭐ Pituitary Support (Targeted Herbal Support)
At Silver Lining Herbs, Pituitary Support is our go-to formula for horses dealing with symptoms of Cushing’s disease.
Benefits:
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Supports a normal endocrine system
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Supports a healthy integumentary system (skin + coat)
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Helps maintain a natural, healthy coat
Recommended For Horses Showing:
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Cushing’s disease (PPID)
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Failure to shed coat
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Excessive or absent sweating
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Frequent urination
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Behavioral changes or aggression
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Slow maturity
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Mares continue to produce milk after weaning
👉 If your horse also shows:
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Cresty neck
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Fatty pockets over the tailhead
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Excessive weight gain
Consider pairing with Thyroid Support for a more complete balance.
How Herbal Support Helps
Rather than forcing a single pathway, herbal support works by:
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Encouraging natural hormone regulation
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Supporting the body’s own feedback systems
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Improving overall resilience and adaptability
This makes it ideal for:
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Long-term maintenance
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Early-stage support
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Supporting alongside traditional therapies
Additional Management Tips for PPID Horses
Nutrition:
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Prioritize a low sugar/starch diet
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Feed high-quality forage
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Limit pasture during high-risk times
Hoof Care:
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Maintain a consistent trimming schedule
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Monitor closely for laminitis
Coat Management:
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Clip long coats to prevent overheating
Routine Monitoring:
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Track water intake, coat changes, and behavior
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Work with your vet on ongoing testing
Can Horses Live Normally with Cushing’s?
Yes—many horses with PPID live full, active lives with proper support.
With the right plan, horses can:
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Maintain a healthy weight
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Regulate coat growth
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Stay rideable and comfortable
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Avoid major complications
Final Thoughts: Don’t Ignore the Subtle Signs
Cushing’s doesn’t always start with dramatic symptoms.
Sometimes it looks like:
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A coat that won’t shed
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A shift in attitude
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Drinking a little more water than usual
Those small changes matter.
👉 The earlier you support the pituitary gland and endocrine system, the better your horse’s outcome.
🌿 Support Starts at the Source
If your horse is showing signs of Cushing’s—or you want to stay ahead of it—Pituitary Support is designed to help bring the body back into balance, naturally.
Because when the endocrine system is supported…everything else follows.
📌 FAQ
What is the first sign of Cushing’s in horses?
One of the earliest signs is delayed shedding or changes in coat texture.
Can younger horses get Cushing’s disease?
Yes, although it is more common in horses over 15.
Is Cushing’s disease curable in horses?
No, but it is highly manageable with proper support and care.
What should I feed a horse with Cushing’s?
A low sugar, forage-based diet with supportive supplementation is recommended.
Does Cushing’s cause laminitis?
Yes, horses with PPID are at a higher risk of developing laminitis.
